Chosen Solution

System is normally on since purchasing new in December 2012. Was working fine yesterday morning but when went to use it last night it was dead. Completely dead - no startup chime no LED on front no sound whatsoever. Took the bottom circular twist cover off and a significant amount of dirt in there. Pretty much a matt filling the circular cover. Disconnected all peripherals and plugged into a known working outlet. No sound, no fan, no HDD, no LED. I suspect either power supply or logic board but open to other ideas. How can I approach this methodically? Can I test for voltage on a power supply cable? (If so, which one, which terminals?)

@mopac01of course you already double checked your outlet and power cord to make sure both are working. Use your multimeter and check for 12V on the wires as described

If yours is different, post some images of what your connector looks like etc. Adding images to an existing question