Chosen Solution

I’m working with a Mac Mini which currently has 2x2GB 1600MHz RAM modules, but I also have 2x8GB 1333MHz RAM modules. Can’t find anything about using lower rate DIMMs. Will this even work?If yes, is it worth quadrupling RAM for a slower frequency?

Sadly, PC3-12800 DDR3 (1600 MHz) is physically different from PC3-10600 DDR3 (1333 MHz). You need to get the proper RAM as the slower won’t fit into the SO-DIMM RAM slots.